Phenolic Compounds

Phenolic Compounds are a large group of secondary metabolites in plants characterized by at least one aromatic ring bearing one or more hydroxyl groups (-OH). They play crucial roles in plant defense, growth regulation, and human health.

Key Features

  • Contain a benzene ring + hydroxyl group(s).
  • Can be simple (phenolic acids) or complex (tannins, flavonoids, lignin).
  • Widely distributed in leaves, fruits, seeds, bark, and roots.

Major Classes & Examples

  • Phenolic acids – caffeic acid, ferulic acid.
  • Flavonoids – quercetin, kaempferol, anthocyanins (pigments in flowers/fruits).
  • Tannins – defense compounds, astringency in tea and wine.
  • Lignin – structural polymer in plant cell walls.
  • Coumarins – anticoagulant and antimicrobial compounds.

Biological Roles in Plants

  • Defense: Antimicrobial, antifungal, insect deterrent.
  • UV Protection: Flavonoids absorb harmful UV rays.
  • Structural Integrity: Lignin strengthens vascular tissue.
  • Attraction: Pigments aid in pollination and seed dispersal.

Health Benefits for Humans

  • Antioxidant: Neutralize free radicals (ROS).
  • Anti-inflammatory: Reduce risk of chronic diseases.
  • Cardioprotective: Lower risk of heart disease.
  • Anticancer: Some phenolics inhibit tumor growth.
  • Neuroprotective: Linked to brain health.